Dr. Medici's research focuses on cell plasticity and its role in mediating the progression of human diseases. In particular, his lab studies how epithelial-mesenchymal transition (EMT) and endothelial-mesenchymal transition (EndMT) contribute to pathological processes such as cancer metastasis, organ fibrosis, and heterotopic ossification. The Medici lab also studies tumor angiogenesis and the mechanisms that give rise to the formation of vascular tumors. Dr. Medici's breakthrough discovery of endothelial-derived stem cells has laid the foundation for a novel approach of using blood vessels to regenerate tissues for the treatment of degenerative diseases, which is currently the primary focus of his lab.

Biography

Dr. Medici is an Assistant Professor of Orthopaedics and Medicine at the Warren Alpert Medical School of Brown University. He received his Ph.D. from Harvard University and did his postdoctoral training at Harvard Medical School and the Beth Israel Deaconess Medical Center. He was an Instructor of Medicine and Developmental Biology at Harvard Medical School prior to joining the faculty at Brown. Dr. Medici is the Director of the Laboratory for Regenerative Medicine and a member of the Cardiovascular Research Center at Rhode Island Hospital. His research interests include cancer biology, vascular biology, skeletal diseases, stem cells and tissue regeneration.