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Jiman He, Ph.D.

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Jiman He

Title: Assistant Professor of Medicine (Research)
Department: Medicine

Jiman_He@brown.edu
+1 401 725 4700

 
Overview | Research |

Biography

My research interests include: (1)Role of tumor suppressor gene PTEN in the development of digestive cancers, and (2) pain medicine.


Selected Publications:

1.He J, de la Monte S, Wands JR. Acute ethanol exposure inhibits insulin signaling in the liver. Hepatology. 2007; 46(6): 1791-1800.
2.He J, de la Monte, Wands J.:The p85 regulatory subunit of PI3K serves as a substrate of PTEN protein phosphoatase activity during insulin mediated signaling.BBRC,397:513-519.
3.DeFidele LM, He J, Bonkowski EL, Han X, Held MA, Bohan A, Menon RK, Denson LA. Tumor Necrosis factor alpha blockade restores growth hormone signaling in murine colitis. Gastroenterology. 2005; 128(5):1278-91.
4.Wang W, Wei T, Luo D, Lin J, Yu Y, Zhao W, Wu B, Chen J, He J: Acute pressure on the sciatic nerve results in rapid inhibition of the wide dynamic range neuronal response. BMC Neuroscience, 2012,13:147.
5.He J, Xu S. Relieving pain upon its onset: a dream? US Surgery. 2008: 6 (1). In press
6.He J, Wu B, Jiang X, Zhang F, Zhao T, Zhang W: A new analgesic method, two-minute sciatic nerve press, for immediate pain relief: a randomized trial. BMC Anesthesiology. 2008: 8:1.

Research Description

My research interests include: (1) the molecular basis of hormone resistance in liver disease, especially the negative effect of PTEN in insulin/PI3K/Akt signaling, and (2) the use of current medical knowledge to elucidate the potential applications of some of the techniques used in traditional Chinese medicine.

Selected Publications:
He J, de la Monte S, Wands JR. Acute ethanol exposure inhibits insulin signaling in the liver. Hepatology. 2007; 46(6): 1791-1800.
DeFidele LM, He J, Bonkowski EL, Han X, Held MA, Bohan A, Menon RK, Denson LA. Tumor Necrosis factor alpha blockade restores growth hormone signaling in murine colitis. Gastroenterology. 2005; 128(5): 1278-91.
He J, Xu S. Relieving pain upon its onset: a dream? US Surgery. 2008: 6 (1). In press
He J, Wu B, Jiang X, Zhang F, Zhao T, Zhang W: A new analgesic method, two-minute sciatic nerve press, for immediate pain relief: a randomized trial. BMC Anesthesiology. 2008: 8:1.