James Klinger, MD
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Title: Associate Professor of Medicine
Department: Medicine
James_Klinger@Brown.EDU
+1 401 444-2776, +1 401 273-7100
Biography
Dr. Klinger completed his fellowship in pulmonary and critical care medicine at Brown University after completing his residency in internal medicine at the Medical College of Pennsylvania. He is currently the Medical Director of the Respiratory Intermediate Care Unit and the Pulmonary Hypertension Center at Rhode Island Hospital. His basic science interests include the natriuretic peptides-cGMP signalling pathway and its role in modulating pulmonary hypertensive and right ventricular hypertrophic responses and pulmonary endothelial barrier function. His clinical research is focused on the use of natriuretic peptides, nitric oxide, and other investigational agents to treat adult patients with pulmonary hypertension. His interests also include treatment and prevention of venous thromboembolism. Dr. Klinger is a member of the pulmonary circulation assembly of the American Thoracic Society and an Associate Editor of the journal "Lung".
Institutions
Rih
Awards
Brown Medical School, Dept. of Medicine, Beckwith Family Award for Outstanding Teaching 2006
Consumers' Research Council of America. "Guide to America's Top Physicians" 2006
Global Directory of Who's Who 2007
Best Doctors in America 2007-2008
Affiliations
American Thoracic Society
American College of Chest Physicians
American Heart Association
American Physiological Society
Society of Critical Care Medicine
Funded Research
Project Title: The role of atrial natriuretic peptide in right ventricular hypertrophy
Role: Principal Investigator
Sponsoring Agency: American Heart Association, Established Investigator Grant
Period of Support: 01/01/02-12/31/05
Amount of Support: $300,000
Project Title: Natriuretic Peptides in Pulmonary Endothelial Barrier Function
Role: Principle Investigator
Sponsoring Agency: NIH-NHLBI HL088328
Period of Support: 6/1/2007-5/31/2012
Amount of Support. $268,781/year.
Project Title: Role of Endothelin-induced PKCd Activation in Right Ventricular Hypertrophy
Role: Mentor
Sponsoring Agency: Actelion Pharmaceutical
Period of Support: 7/1/2008-6/30/2009
Amount of Support. $75, 000
Teaching Experience
Biomed 195 Research Instructor
Independent Study Research Mentor
Summer Research Early Identification Mentor
Biomed 209 Topics in Respiratory Physiology, Co-Director
Biomed 350 Pulmonary Pathophysiology, Lecturer
Biomed 284/286B Cell Pathology, Lecturer

