William G. Cioffi, Jr., M.D. is professor and chair of the Department of Surgery at Brown Medical School. He is a national leader in trauma, critical care, and burns. Throughout his career his major research interests have focused on the host response to injury and include basic science, translational, and clinical research.

Biography

Hospital Appointments

Executive Surgeon-in-Chief, Department of Surgery, The Miriam Hospital, Veterans Affairs Hospital,
Women and Infants Hospital and Memorial Hospital of Rhode Island.

2001-present Surgeon-in-Chief, Department of Surgery
Rhode Island Hospital, Providence, RI

1995-present Active Surgeon
Women & Infants' Hospital, Providence, RI

Institutions

Rih

Research Description

William G. Cioffi, Jr., M.D. is professor and chair of the Department of Surgery at Brown Medical School. He is a national leader in trauma, critical care, and burns. Throughout his career his major research interests have focused on the host response to injury and include basic science, translational, and clinical research.

Awards

2006 Distinguished Academic Achievement Award, University of Vermont College of Medicine

2004 History Maker, Rhode Island Historical Society

2002, 2003, 2004, 2005, 2006 America's Top Doctors, Castle Connolly Medical Ltd., New York, NY

1995 Residents Teaching Award, Rhode Island Hospital and Brown University, Providence, RI

1985 Vermont State Residents Trauma Competition, American College of Surgeons Committee on Trauma – First Place

1984 Vermont State Residents Trauma Competition, American College of Surgeons Committee on Trauma – First Place

1981 Surgical Residents Research Prize, Department of Surgery, University of VT

1981 Alpha Omega Alpha

Affiliations

2003 – present Boston Surgical Society
2002 – present International Surgical Group (ISG)
1999 – present The Halsted Society
1999 – present American Surgical Association (ASA)
1999 – present American Board of Surgery
1998 – present Brain Injury Association of Rhode Island
1998 – present Southern Surgical Association (SSA)
1998 – present International Association for Surgical Metabolism and Nutrition (IASMEN)
1997 – present Shriners Hospitals for Children – Research Advisory Board
1997 – present New England Surgical Society (NESS)
1997 – 2003 American College of Surgeons Committee on Trauma
1997 – 2002 Rhode Island Committee on Trauma – Chairman
1996 – present International Society of Surgery, US Chapter (ISS)
1996 – present International Association for the Surgery of Trauma and Surgical Intensive Care (IATSIC)
1995 – present Shock Society
1994 – present Rhode Island Medical Society
1994 – present Providence Medical Association
1994 – present Providence Surgical Society
1994 – present North American Burn Society (NABS)
1994 – present American College of Surgeons – Rhode Island Chapter
1993 – Third Sino–American Burn/Trauma Conference –Organizing Committee
1993 – present Society of University Surgeons (SUS)
1993 – present International Society of Burn Injuries (ISBI)
1992 – present Surgical Infection Society
1992 – 1994 American College of Surgeons – Southwest Texas Chapter
1991 – present Society of Critical Care Medicine (SCCM)
1991 – present American Burn Association
1991 – present American Association for the Surgery of Trauma
1990 – present Surgical Biology Club III
1990 – present American College of Surgeons
1988 – present John H. Davis Surgical Society
1987 – present Association for Academic Surgery (AAS)
1986 – 1990 San Antonio Surgical Society

Funded Research

ONGOING RESEARCH SUPPORT

National Institutes of Health (NIH)/National Institute on Alcohol Abuse and Alcoholism (NIAAA) #2 R01 AA009892-11A1
Peter Monti (PI)
Role: Collaborator
$2,133,733.
05/10/05 to 04/30/10
"Enhanced MI with alcohol positive trauma patients"
The major goal of this project is to evaluate the efficacy of motivational interviews with significant others, in preventing recidivism among alcohol-positive patients admitted to a trauma service.

NIH / National Institute of General Medical Sciences (NIGMS) #1 T32 GM065085-1A1
Jorge Albina (PI)
Role: Executive Committee, Clinical Coordinator, Research Faculty
$1,201,764.
07/01/2004 to 06/30/09
"Trauma and Inflammation Research Training"
The major goal of this project is to identify, recruit, and train the next generation of Trauma Scientists with particular emphasis in retaining MDs in academic trauma medicine careers.

NIH #5 RO1 HL 073525-02.
Alfred Ayala (PI)
Role: Collaborator
$1,431,210 (direct and indirect costs).
9/1/03-6/30/07
Regulatory mechanisms of acute lung injury.

View My Full Publication List in pdf format

Selected Publications

• Safran H, Dipetrillo T, Iannitti D, Quirk D, Akerman P, Cruff D, Cioffi W, Shah S, Ramdin N, Rich T: Gemcitabine, paclitaxel, and radiation for locally advanced pancreatic cancer: a Phase I trial. International Journal of Radiation Oncology, Biology, Physics. 54(1):137-41, 2002 Sep 1.(2002)
• Song GY, Chung CS, Jarrar D, Cioffi WG, Ayala A: Mechanism of immune dysfunction in sepsis: Inducible nitric-oxide mediated alterations in p38 MAPK activation. J Trauma 53(2):276-83, 2002.(2002)
• Knoferl MW, Angele MK, Diodato MD, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate of subsequent sepsis. Ann Surg 235(1):105-12, 2002.(2002)
• Knoferl MW, Diodato MD, Schwacha MG, Cioffi WG, Bland KI, Chaudry IH: Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis. Shock 16(6):479-83, 2001.(2001)
• Cioffi WG: Whatís new in burns and metabolism [review]. J Am Coll Surg 192(2):241-254, 2001.(2001)
• Safran H, Moore T, Iannitti D, DePetrillo T, Akerman P, Cioffi W, Harrington D, Quirk D, Rathore R, Cruff D, Vakharia J, Vora S, Savarese D, Wanebo H: Paclitaxel and concurrent radiation for locally advanced pancreatic cancer. Int J Radiation Oncology Biol Phys 49(5):1275-1279, 2001.(2001)
• Wang P, BA ZF, Koo DJ, Cioffi WG, Bland KI, Chaudry IH: Continuous resuscitation after hemorrhage and acute fluid replacement improves cardiovascular responses. Surgery 129(5):559- 66, 2001.Rocco Jr TR, Reinert SE, Cioffi WG, Harrington DT, Buczko G, Simms HH: A 9-year, singleinstitution, retrospective review of death rate and prognosis factors in adult respiratory distress syndrome. Ann Surg 233(3):414-422, 2001.Saitoh D, Shirani KZ, Cioffi WG, Kizaki T, Ohmo H, Okada Y, Mason AD Jr, Pruitt BA Jr: Changes in the tissue and plasma superoxide dismutase (SOD) levels in a burned rat model. Tohoku J Experimental Med 193(1):27-36, 2001.(2001)