Gaurav Choudhary, MD, assistant professor
of medicine, has received $75,000 for “Role
of Endothelin-Induced PKC delta Activation
in Right Ventricular Hypertrophy,”
an Actelion Pharmaceuticals Young Investigator
Award. The project runs for one
year. James Klinger, associate professor of
medicine and staff pulmonologist at Rhode
Island Hospital, is principal investigator
and mentor for Choudhary’s work.
Co-investigator is Elizabeth Harrington,
associate professor of medicine (research).
Susan A. Gerbi, PhD, professor of biology,
is principal investigator of a $600,000 grant
from the Susan Komen Foundation for two
projects related to breast cancer research
for a three-year period. Collaborators
include Alex Brodsky, PhD, and Benjamin
Raphael.
Michelle A. Lally, MD, assistant professor
of medicine, is principal investigator of the
Adolescent Trials Network (ATN): Adolescent
Medicine Leadership Group grant,
funded from March 2008 through February
2011 in the amount of $27,000 per annum.
This grant is to support the Adolescent
Medicine Leadership Group in the formulation
of hypotheses and review of proposals
submitted to the Network for scientific merit
and feasibility. The primary mission of the
ATN is to explore promising new modalities
in HIV-infected and HIV at-risk adolescents,
ages twelve through twenty-four.
Barry M. Lester, PhD, professor of
psychiatry and human behavior and
pediatrics, received $2,212,572 from the
National Institute on Drug Abuse and the
National Institute of Mental Health
for “Maternal Lifestyle Study Phase 5.”
The grant runs through March 2011.
Kenneth H. Mayer, MD, professor of medicine
and community health, is principal
investigator of a NIH/NIAID Harvard
Medical School Vaccine Clinical Trials Unit.
The period of funding is January 2008 to
December 2008 in the amount of $357,617.
Linda Resnik, PT, PhD, OCS, assistant
professor (research) of community health
and research health scientist at the
Providence VA Medical Center, was awarded
$1,112,000 from VA HSR&D for a Merit
Review study titled “A Computer Adaptive
Test to Measure Community Reintegration.”
The objectives of this study are to develop
the Community Reintegration of Injured
Service Member measure into a computer
adaptive test that will facilitate efficient yet
comprehensive collection of community
re-integration data. The study will run
through May 2011.
Damaris Rohsenow, PhD, associate director
of the Center for Alcohol and Addiction
Studies (CAAS) and professor (research) of
community health, with co-investigators Jennifer Tidey, PhD, assistant professor of
psychiatry and human behavior; Rosemarie
Martin, PhD, assistant professor of community
health (research); Peter Monti, PhD,
director of CAAS, and Robert Swift, MD,
PhD, professor of psychiatry and human
behavior, has been awarded a grant titled
“Varenicline and motivational advice for
smokers with SUD” from the NIDA, June
15, 2008 through March 31, 2013, to conduct
a randomized clinical trial of a smoking
medication for efficacy with smokers in
treatment for substance dependence.
Stephen Salloway, MD, MS, professor of
clinical neurosciences and psychiatry and
director of the Memory and Aging
Program, Butler Hospital, has received
$790,649 from Wyeth for a phase IIa, multicenter,
randomized multiple ascending
dose, safety, tolerability and immunogenicity
trial of ACC-001 with QS-21 adjuvant
(amyloid vaccine trial) in patients with
mild to moderate Alzheimer’s disease. He
received $244,048 from Elan Pharmaceuticals
for a randomized, double-blinded, placebocontrolled,
dose-ranging, safety, and
efficacy study of oral ELND005 (AZD-103)
in Alzheimer’s disease, and $519,998 for a
phase III, multicenter, randomized, doubleblind,
placebo-controlled, efficacy and
safety trial of bapineuzumab (AAB-001,
ELN115727) in patients with mild-moderate
Alzheimer’s disease who are apolipoprotein
Ee4 carriers and non-carriers.
Juan Sanchez-Esteban, MD, assistant
professor of pediatrics, has received an
NIH R01 grant for “Mechanotransduction
and Lung Alveolar Differentiation” in the
amount of $1,256,584. The project runs
from May 1, 2008 through April 30, 2013.
Barbara Stonestreet, MD, professor of
pediatrics, was awarded an R01 grant for
“Cytokines and the blood-brain barrier in
the ovine fetus” from the National Institute
of Child Health and Human Development.
The $1,471,412 grant runs from 2008
through 2013.
Robert Swift, MD, PhD, professor of
psychiatry and human behavior and
a member of the Center for Alcohol and
Addiction Studies, is the site principal
investigator for a two-year clinical research
study, “Prazosin and Combat Trauma
PTSD,” funded by the Department of
Veterans Affairs. The amount of funding
is $250,000. Co-investigators are Amir
Khan, MD, and Christy Capone, PhD.
Haiyan Xu, MD, PhD, assistant professor
of medicine (research), has been awarded
an American Heart Association Scientist
Development Grant for “Mechanism and
consequence of obesity-related adipose
macrophage infiltration” in the amount of
$308,000. The grant runs from January 1,
2008 through December 31, 2011.
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