Grants

Gaurav Choudhary, MD, assistant professor of medicine, has received $75,000 for “Role of Endothelin-Induced PKC delta Activation in Right Ventricular Hypertrophy,” an Actelion Pharmaceuticals Young Investigator Award. The project runs for one year. James Klinger, associate professor of medicine and staff pulmonologist at Rhode Island Hospital, is principal investigator and mentor for Choudhary’s work. Co-investigator is Elizabeth Harrington, associate professor of medicine (research).
Susan A. Gerbi, PhD, professor of biology, is principal investigator of a $600,000 grant from the Susan Komen Foundation for two projects related to breast cancer research for a three-year period. Collaborators include Alex Brodsky, PhD, and Benjamin Raphael.
Michelle A. Lally, MD, assistant professor of medicine, is principal investigator of the Adolescent Trials Network (ATN): Adolescent Medicine Leadership Group grant, funded from March 2008 through February 2011 in the amount of $27,000 per annum. This grant is to support the Adolescent Medicine Leadership Group in the formulation of hypotheses and review of proposals submitted to the Network for scientific merit and feasibility. The primary mission of the ATN is to explore promising new modalities in HIV-infected and HIV at-risk adolescents, ages twelve through twenty-four.
Barry M. Lester, PhD, professor of psychiatry and human behavior and pediatrics, received $2,212,572 from the National Institute on Drug Abuse and the National Institute of Mental Health for “Maternal Lifestyle Study Phase 5.” The grant runs through March 2011.
Kenneth H. Mayer, MD, professor of medicine and community health, is principal investigator of a NIH/NIAID Harvard Medical School Vaccine Clinical Trials Unit. The period of funding is January 2008 to December 2008 in the amount of $357,617.
Linda Resnik, PT, PhD, OCS, assistant professor (research) of community health and research health scientist at the Providence VA Medical Center, was awarded $1,112,000 from VA HSR&D for a Merit Review study titled “A Computer Adaptive Test to Measure Community Reintegration.” The objectives of this study are to develop the Community Reintegration of Injured Service Member measure into a computer adaptive test that will facilitate efficient yet comprehensive collection of community re-integration data. The study will run through May 2011.
Damaris Rohsenow, PhD, associate director of the Center for Alcohol and Addiction Studies (CAAS) and professor (research) of community health, with co-investigators Jennifer Tidey, PhD, assistant professor of psychiatry and human behavior; Rosemarie Martin, PhD, assistant professor of community health (research); Peter Monti, PhD, director of CAAS, and Robert Swift, MD, PhD, professor of psychiatry and human behavior, has been awarded a grant titled “Varenicline and motivational advice for smokers with SUD” from the NIDA, June 15, 2008 through March 31, 2013, to conduct a randomized clinical trial of a smoking medication for efficacy with smokers in treatment for substance dependence.
Stephen Salloway, MD, MS, professor of clinical neurosciences and psychiatry and director of the Memory and Aging Program, Butler Hospital, has received $790,649 from Wyeth for a phase IIa, multicenter, randomized multiple ascending dose, safety, tolerability and immunogenicity trial of ACC-001 with QS-21 adjuvant (amyloid vaccine trial) in patients with mild to moderate Alzheimer’s disease. He received $244,048 from Elan Pharmaceuticals for a randomized, double-blinded, placebocontrolled, dose-ranging, safety, and efficacy study of oral ELND005 (AZD-103) in Alzheimer’s disease, and $519,998 for a phase III, multicenter, randomized, doubleblind, placebo-controlled, efficacy and safety trial of bapineuzumab (AAB-001, ELN115727) in patients with mild-moderate Alzheimer’s disease who are apolipoprotein Ee4 carriers and non-carriers.
Juan Sanchez-Esteban, MD, assistant professor of pediatrics, has received an NIH R01 grant for “Mechanotransduction and Lung Alveolar Differentiation” in the amount of $1,256,584. The project runs from May 1, 2008 through April 30, 2013. Barbara Stonestreet, MD, professor of pediatrics, was awarded an R01 grant for “Cytokines and the blood-brain barrier in the ovine fetus” from the National Institute of Child Health and Human Development. The $1,471,412 grant runs from 2008 through 2013.
Robert Swift, MD, PhD, professor of psychiatry and human behavior and a member of the Center for Alcohol and Addiction Studies, is the site principal investigator for a two-year clinical research study, “Prazosin and Combat Trauma PTSD,” funded by the Department of Veterans Affairs. The amount of funding is $250,000. Co-investigators are Amir Khan, MD, and Christy Capone, PhD.
Haiyan Xu, MD, PhD, assistant professor of medicine (research), has been awarded an American Heart Association Scientist Development Grant for “Mechanism and consequence of obesity-related adipose macrophage infiltration” in the amount of $308,000. The grant runs from January 1, 2008 through December 31, 2011.