Subacromial Impingement syndrome (ie. subacromial bursitis and rotator cuff tendinitis) is one of the most common musculoskeletal complaints. Chemokines and their receptors (SDF-1, IL-1) present in the subacromial bursa are important in mediating the inflammation that occurs in subacromial bursitis. By targeting inhibition of the SDF-1/IL-1 pathway, new pharmacologic agents, with fewer side effects than NSAIDs and steroids, may be designed to treat this most common and painful condition.

Research Description

RESEARCH IN PROGRESS

A. Blaine as PI
1. Chemokine Expression and Inhibition in Subacromial Bursitis and Rotator Cuff Disease. R03 grant submitted to NIH.
2. IL1- beta induces Expression of Stromal Derived Factor-1 in Subacromial Bursal Cells, submitted to JOR
3. CXCR4 blockade (AMD 3100 and T140 analog) inhibits SDF-1α expression and cell migration in human subacromial bursa cells, submitted to JOR

B. Collaborations
1. Mt. Sinai Medical Center, NY, NY (Parson B): Tuberosity healing after humeral head replacement arthroplasty with a trabecular metal prosthesis.
2. Brown Bioengineering (Webster T): Nanoscale surface modification of orthopaedic biomaterials (PEEK and Titanium) improves bony ingrowth in a rat calvarial model.
3. RIH Emergency Medicine (Jay G): Impaired Lubricin expression in the pathophysiology of adhesive capsulitis
4. Columbia University Shoulder study Group (Levine WN, Bigliani LU): A Multicenter Study of the Bigliani/Flatow Complete Shoulder Solution, final data collection in progress.

C. Resident Projects
1. Zimmermann M: Cartilage Differentiation in the Coracoacromial Ligament in Patients with Impingement Syndrome, Submitted paper to JSES.
2. Got C, Green A: Biomechanical comparison of parallel vs. 90 - 90 plating of bicolumn distal humerus fractures with intra-articular comminution, submitted to AAOS, manuscript in preparation.
3. Aaron D: CXCR4 Inhibition in an animal(rat) model of subacromial bursitis and rotator cuff disease. IRB, IACUC done. Experiments in progress.
4. Mulcahey M: Factors important in healing of the glenoid labrum after shoulder dislocation. IRB, IACUC done. Data collection. Grant in preparation. Experiments in preparation.
5. Behrens S: Nanoscale surface modification of orthopaedic biomaterials (PEEK and Titanium) improves bony ingrowth in a rat calvarial model. IRB, IACUC done.
6. Kamal R: Randomized controlled trial of intraarticular versus subtendinous injection of corticosteroid in lateral epicondylityis. 16/40 patients enrolled.

Awards

POSTGRADUATE HONORS AND AWARDS

1. AOA ABC Traveling Fellowship, Finalist, elected as Alternate, 2011.
2. Elected to Best Doctors in America, Best Doctors, Inc., Boston, MA, 2007-2008, 2009-2010.
3. Aircast Award, Best Paper: Edwards SL, Packer JD, Lee JA, Bell JE, Ahmad CS, Levine WN, Bigliani LU, Blaine TA: Superior Results with Non-operative Management of Superior Labral Tears., AOSSM Annual Meeting, Calgary, CAN, July, 2007
4. Traveling Fellow, elected First Alternate, American Shoulder and Elbow Society (ASES), 2007.
5. Medical Student Certificate of Appreciation, Columbia University College of Physicians and Surgeons, 2002.
6. Zimmer Travel Award, American Orthopaedic Association (AOA), Boca Raton, FL, June 1997.
7. Surgical Scholars, The University of Connecticut School of Medicine, 1993.
8. Elected to Sigma Xi Scientific Research Society, 1991.

OTHER AWARDS
1. eNews Featured Alumnus, Avon Old Farms Preparatory School, Avon, CT March, 2009
2. Athletic Hall of Fame Inductee, Lacrosse, Avon Old Farms School, Avon, CT, May, 2009.

Affiliations

MEMBERSHIP IN SOCIETIES

1. American Shoulder and Elbow Society (ASES), Active member, elected 2009.
2. American Orthopaedic Association (AOA), Member since June 13, 2007.
3. American Shoulder and Elbow Society (ASES), Associate member, elected 2005.
4. American Orthopaedic Association (AOA), Emerging Leaders Program, 2004-2007.
5. American Orthopaedic Society for Sports Medicine (AOSSM), member since July 2003.
6. Arthroscopy Association of North America (AANA), member since May 2007.
7. American Academy of Orthopaedic Surgeons (AAOS), member since 2004.
8. Columbia Shoulder Society, member since 2000.
9. Mayo Elbow Club, member since 1999.
10. Orthopaedic Research Society (ORS), member since 1997.
11. American Society of Bone and Mineral Research (ASBMR), member since 1997.
12. Sigma Xi Scientific Research Society, member since 1991.

Funded Research

PEER-REVIEWED GRANTS


1. NIH RO3 Grant Application: Chemokine Expression and Inhibition in Subacromial Bursitis and Rotator Cuff Disease, ($150,000). Principal Investigator, submitted June 2010.

2. Mentor, OREF Resident Educational Grant: Factors important in healing of the glenoid labrum after shoulder dislocation. PI: Mary Mulcahey MD, Mentor: Theodore Blaine MD, Submitted, under review, 2009.

3. NIH National Institutes of Health Center of Biomedical Research Excellence (COBRE) for Skeletal Health and Repair - Pilot Project Grant Program: Chemokine expression and regulation in human subacromial bursa, ($50,000), Principal Investigator, Funding Period Nov. 1, 2008- Nov. 2010.

4. Orthopaedic Research and Education Foundation (OREF) Research Grant: Developing New Therapeutics to Replace NSAIDs and Steroids in the Treatment of Subacromial Impingement: Chemokine Expression And Regulation In Subacromial Bursitis And Rotator Cuff Disease, ($100,000), Principal Investigator, Funding Period Jan. 2006- Jan. 2008.

5. InSCOPE Orthopaedic Fellowship Award, The Pathophysiology Of Glenohumeral Joint Arthritis And Rotator Cuff Disease, ($50,000) Principal Investigator, Jan. 2006- Jan. 2007.

6. InSCOPE Orthopaedic Fellowship Award, The molecular pathophysiology of rotator cuff disease. ($25,000) Principal Investigator, January 2005-2006.

7. ASES Research Grant, Cytokine expression in subacromial bursitis and rotator cuff disease, ($10,000) Principal Investigator, January 2005-2006.

8. OREF Resident Research Grant (Sponsor) PTH (Forteo) Effects on Fracture Healing in Patients with Osteoporotic Fractures of the Proximal Humerus, Mentor and Advisor, ($15,000) Jan. 2004-2006.

9. NIH Medical Student Summer Research Grant, PTH (Forteo) Effects on Fracture Healing in Patients with Osteoporotic Fractures of the Proximal Humerus, ($4,000) Mentor and Advisor, May 2003 – October 2003.

10. Irving Center Clinical Research Grant, PTH (Forteo) Effects on Fracture Healing in Patients with Osteoporotic Fractures of the Proximal Humerus, ($10,000) Principal Investigator, period May 2003 – October 2003.

11. Arthroscopy Association of North America (AANA) Grant, March 2001, Inflammatory mediators in subacromial bursitis and impingement syndrome. ($15,000) Senior Investigator, April 2001 to April 2002.

12. American Orthopaedic Association (AOA) Zimmer Travel Award, Modulation of cytokine production in titanium stimulated human monocytes by pharmacologic agents: the role of cAMP signaling mechanisms. Boca Raton, FL., June 1997.

13. The American Fracture Association (AFA) Resident Research Grant, May 1997 The biochemical basis for fracture healing: the role of inflammatory cytokines in fracture union and non-union. ($3,000) Principal Investigator, June 1997-99.

14. OREF Resident Research Grant, Orthopaedic Research & Education Foundation, 1994, ($15,000) Heterotopic Ossification. 1994-95.

NON PEER-REVIEWED GRANTS

1. Zimmer Clinical Study Grant, A Multicenter Study of the Bigliani/Flatow Complete Shoulder Solution, ($700,000) Principal Investigator, February 2001 to 2007.

Selected Publications

• Editor, Shoulder Arthroplasty 2nd Edition, DVD, American Academy of Orthopaedic Surgeons, 2010(2010)
• Edwards, S, Blaine TA, Bell, JE, Marion CJ, and Bigliani LU: Minimally invasive approach for shoulder arthroplasty in Minimally Invasive Surgery in Orthopaedics, Eds: Scuderi G., Tria A., and Berger R., pps. Springer 2010.(2010)
• Blaine, TA, Green A, and Bigliani LU: Bankart repair and inferior capsular shift, in Operative Techniques in Orthopaedic Surgery: Shoulder and Elbow, Eds.: Wiesel S, (sections eds. Ramsey M and Williams G,) Lippincott Williams Wilkins, In Press, 2010.(2010)
• Gosselin M, Mulcahey M, and Blaine TA: Diagnosis and Management of Chronic Shoulder Pain, JOURNAL OF MUSKULOSKELETAL MEDICINE, In Press, 2010.(2010)
• Bell JE, Packer JD, Lee JA, Edwards SL, Ahmad CS, Levine WN, Bigliani LU, Blaine TA: The Operative Management of Rotator Cuff Disease Results in Superior Pain Relief and Functional Improvement Compared to Nonoperative Treatment. JOURNAL OF BONE AND JOINT SURGERY, Under revision, 2010.(2010)
• Zimmerman M, Morgan B, Bauer G, Lee FY, O'Keefe RJ, Bigiani LU, and Blaine TA: Cartilage Differentiation in the Coracoacromial Ligament in Patients with Impingement Syndrome, JOURNAL SHOULDER ELBOW SURG., In preparation, 2010.(2010)
• Fujisawa M, Blaine TA, Minematsu H, Lee FY, Levine WN, and Bigliani LU: Repetitive Mechanical stress simulated subacromial impingement induces activation of inflammatory molecules in human subacromial bursa cells, JOURNAL OF ORTHOPAEDIC RESEARCH, submitted, 2010.(2010)
• Got C, Shuck J, Biercevicz A, Paller D, Zimmermann M, Mulcahey M, Blaine TA, Green A: Biomechanical comparison of parallel vs. 90 - 90 plating of bicolumn distal humerus fractures with intra-articular comminution, J. SHOULDER ELBOW SURG, in preparation, 2010.(2010)
• Proto A, Bigliani LU, Lee FY and Blaine TA: IL1- beta induces Expression of Stromal Derived Factor-1 in Subacromial Bursal Cells, J. ORTHOPAEDIC RESEARCH, submitted, 2010.(2010)
• Blaine, T A; Cote, M A; Ortega, S.; Lee, F Y; Bigliani, L U; Chen, Q CXCR4 blockade (AMD 3100 and T140 analog) inhibits SDF-1α expression and cell migration in human subacromial bursa cells, J. ORTHOPAEDIC RESEARCH, submitted 2010.(2010)
• Edwards SL, Packer JD, Lee JA, Bell JE, Ahmad CS, Levine WN, Bigliani LU, Blaine TA: Superior Results with Non-operative Management of Superior Labral Tears. AMERICAN JOURNAL OF SPORTS MEDICINE, Accepted, in press, 2010.(2010)
• Blaine TA: Anatomy and Surgical Approaches, ASES Elbow Curriculum for Elbow Disorders, In preparation, 2010.(2010)
• Blaine, TA and Edwards,S: Non-arthroplastic treatment of glenohumeral arthritis, in Orthopedic Knowledge Update, Shoulder and Elbow 3 Ed. Leesa Galatz, pps. 353-9, 2008.(2008)
• Barwood S, Blaine TA, Setter KJ, Lee, J., Levine, WN, Wiater JM, and Bigliani LU: The Low Prevalence of Early Radiolucencies About A Pegged Glenoid Component Using Cement Pressurization, J SHOULDER ELBOW SURG., 17: 703-708, 2008.(2008)
• Blaine TA, Moskowitz R, Udell J, Skyhar M, Levin R, Friedlander J, and Altman R, on behalf of the HUPS Clinical Study Group: Treatment of persistent shoulder pain due to osteoarthritis, rotator cuff tear, and/or adhesive capsulitis with HYALGAN: A randomized, controlled trial. JOURNAL BONE AND JOINT SURG.90A: 970-979, May 2008.(2008)
• Packer, JD., Nguyen, D., Kippe, MA., and Blaine, TA: Lateral epicondylitis, in The Athlete's Elbow, AAOS Monograph Series 39, pps. 17-25, 2008.(2008)
• Blaine TA, O'Driscoll SW, Umansky SC and Kibler, WB: Management of Distal Humerus Malunions in Advanced Reconstruction: Elbow, Eds. Yamaguchi K, King GJW, McKee MD and O'Driscoll SW., 363-374, AAOS, 2007.(2007)
• Edwards S. and Blaine TA: Single-Row Arthroscopic Rotator Cuff Repair, in Minimally Invasive Shoulder and Elbow Surgery, Eds.: Levine W, Blaine TA, and Ahmad CS. Informa Healthcare USA, New York, NY, pps. 231-46, 2007.(2007)
• Minematsu H, Shin MJ, Celil Aydemir AB, Seo SW, Kim DW, Blaine TA, Macian F, Yang J, Young-In Lee, F: Orthopedic implant particle-induced tumor necrosis factor-alpha production in macrophage-monocyte lineage cells is mediated by nuclear factor of activated T cells, ANN N Y ACAD SCI. 2007 Nov;1117:143-50.(2007)
• Levine WN, Kashyap, CP, Bak, SF, Ahmad, CS, Blaine, TA, and Bigliani, LU: Non-operative management of idiopathic adhesive capsulitis, J SHOULDER ELBOW SURG., 16 (5): 569-73, 2007. Epub 2007 May 24.(2007)
• Editor, Minimally Invasive Shoulder and Elbow Surgery, Eds.: Levine W, Blaine TA, and Ahmad CS. Informa Healthcare USA, New York, NY, 2007.(2007)
• Brown G, Ankem HK, Bell JE, and Blaine TA: Elbow Arthroscopy: Loose Body Removal and Synovial Plica Debridement, in Minimally Invasive Shoulder and Elbow Surgery, Eds.: Levine W, Blaine TA, and Ahmad CS. Informa Healthcare USA, New York, NY, pps. 331-40, 2007.(2007)
• Bell J, Edwards S, and Blaine TA: Surgical Approaches to the Shoulder in Adult Reconstructive Surgery, Eds Daniel Berry and Scott Steinman, Lippincott Williams and Wilkins, pps. 213-219, 2007.(2007)
• Blaine, TA., Bell, JE, and Edwards, S.: Minimally Invasive Total Shoulder Arthroplasty: Surgical technique video. AAOS 2007 Annual Meeting, San Diego, CA, 2007. http://www4.aaos.org/product/productpage.cfm?code=17114(2007)
• Edwards S, Bell, JE, and Blaine TA: Inflammation and shoulder pain – A perspective on rotator cuff disease, adhesive capsulitis, and osteoarthritis. Touch Briefings, 2006. http://www.touchbriefings.com/musculoskeletal.htm(2006)
• Blaine TA, Voloshin I, and Bigliani LU: Minimally invasive approach for shoulder arthroplasty in MIS Techniques in Orthopaedics, Eds: Scuderi G., Tria A., and Berger R., Springer 2006.(2006)
• Blaine, TA: Mini-incision shoulder arthroplasty, Orthopedics Today. 2006, 26:18.(2006)
• Ugwonali, O and Blaine TA: Acromioclavicular Joint Reconstruction, TECHNIQUES IN SHOULDER AND ELBOW SURGERY. 7(1):27-35, March 2006(2006)
• Levine, WN, Soong M, Ahmad C, Blaine TA, and Bigliani LU: Arthroscopic distal clavicle resection: A comparison of bursal and direct approaches. ARTHROSCOPY, 22(5): 516-520, 2006.(2006)
• Fujisawa M, Blaine TA, Ankem HK, Moon YL, Kim YS, Bigliani LU and Masatoshi N: Repetitive subacromial impingement induces inflammatory molecules. An in vitro study with human subacromial bursal cells: JAPANESE JOURNAL OF ORTHOPAEDIC SPORTS MEDICINE 26(1): 85, 2006.(2006)
• Kim YS, Bigliani LU, Fujisawa M, Murakami K, Chang SS, Lee HJ, Lee FY, Blaine TA:: Stromal Cell-Derived Factor 1 (Sdf-1; Cxcl12) Is Increased In Subacromial Bursitis And Downregulated By Steroid and Non-steroidal Anti-inflammatory Agents. J. ORTHOP. RES, 24(8): 1756-1764, 2006.(2006)
• Shoulder Arthroscopy, Ed.: Blaine, TA, American Academy of Orthopaedic Surgeons Monograph Series, 2006.(2006)
• Blaine TA and Miller S.: Subacromial Decompression/Rotator Cuff Repair, in: Shoulder Arthroscopy, Ed.: Blaine, TA, American Academy of Orthopaedic Surgeons Monograph Series, 2006.(2006)
• Emerging Options in Osteoarthritis Pain, CME Teleconference, Haymarket Medical Series, Sept – Dec, 2006.(2006)
• Recent advances in the treatment of chronic shoulder pain, Research Report with Frank Fields, Telecare, May 24, 2005.(2005)
• Blaine, TA and Bigliani, LU: Rotator Cuff Disorders in Tendon Injuries: Basic Science and Clinical Medicine, Eds. Maffulli N, Renstrom P and Leadbetter WB, Springer-Verlag, London, 2005.(2005)
• Moskowitz R and Blaine TA: An Overview of Treatment Options for Persistent Shoulder Pain, AMERICAN JOURNAL OF ORTHOPAEDICS, Am J Orthop. 2005 Dec;34(12 Suppl):10-5.(2005)
• Liao, T., Yurgelan, M., Chang, SS., Zhang, HZ., Murakami, K., Blaine, TA, Parisien, M., Kim, W., Winchester, RJ., and Lee, FY.: Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone. J. ORTHOP. RES., 23(1): 203-9, Jan. 2005.(2005)
• Blaine, TA, Adams, RA, and Morrey, BF: Conversion of Interposition Arthroplasty to Semi-constrained Total Elbow Arthroplasty in Elbow Arthritis, JOURNAL OF BONE & JOINT SURGERY, 87-A (2); 286-92, Feb., 2005.(2005)
• Lee, FY, Kim DW, Karmin JA, Hong, D, Chang SS, Fujisawa M, Takayanagi H, Bigliani LU, Blaine TA, and Lee HJ: micro-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells, J BIOL CHEM. 2005 Aug 19;280(33):29929-36. Epub 2005 Jun 13.(2005)
• Voloshin I, Gelinas J, Maloney M, O'Keefe RJ, Bigliani LU, and Blaine TA: Pro-inflammatory cytokines and metalloproteases are expressed in the subacromial bursa in patients with rotator cuff disease. ARTHROSCOPY, 21(9); 1076, 2005.(2005)
• Blaine TA, Kim YS, Voloshin I, Chen D, Murakami K, Chang SS, Winchester R, Lee FY, O'Keefe RJ, and Bigliani LU: The molecular pathophysiology of subacromial bursitis in rotator cuff disease, J. SHOULDER AND ELBOW SURGERY, 14 (1S): 84S-89S, Feb., 2005.(2005)
• Ankem H and Blaine TA: Revision Shoulder Arthroplasty, TECHNIQUES IN SHOULDER AND ELBOW SURGERY. 6(4):189-198, December 2005.(2005)
• Setter KS, Voloshin I, and Blaine TA, Pre-Operative Evaluation and Surgical Approaches in Shoulder Arthroplasty, Eds. Bigliani LU and Flatow EL, Springer-Verlag, New York, 2005.(2005)
• Surgical Management of Osteoarthritis, Episode 412, PBS Documentary, ITV, June 2005.(2005)
• Setter, K., Blaine, TA. and Rosenwasser, M. : Management of the Stiff Elbow, Orthopaedic Knowledge Online, 2005. http://www5.aaos.org/oko/shoulder_elbow/stiff_elbow/pathophysiology/pathophysiology.cfm(2005)
• Blaine TA, Levine WN, Bigliani LU: Fractures of the Proximal Humerus in The Shoulder, 3rd Edition, Editors: Charles A. Rockwood, Jr. and Frederick A. Matsen, III, MD, W.B. Saunders., 2004.(2004)
• Editor, Shoulder Section in Essentials of Muskuloskeletal Imaging, Eds. Johnson TR and Steinbach LS, AAOS, 2004.(2004)
• Sanchez-Sotelo J, Barwood S, and Blaine TA: Current Concepts in Elbow Fracture Care, CURR. OPIN. ORTHOP., 15 (4): 300-310, August, 2004.(2004)
• Carroll RM, Izquierdo R, Vazquez M, Blaine TA, Levine WN, Bigliani LU: Conversion of failed hemiarthroplasty to total shoulder arthroplasty for glenoid arthrosis. JOURNAL OF SHOULDER AND ELBOW SURGERY. 13(6): 599-603, 2004.(2004)
• Chang, SS., Suratwala, S., Jung, KM., Doppelt, J., Zhang, HZ., Blaine, TA., Kim, TW., Winchester, RJ., and Lee, FY.: Bisphosphonates may reduce recurrence in giant cell tumor of bone by inducing apoptosis. CLIN. ORTHO. REL RES., 426: 103-9, 2004.(2004)
• Editor, Elbow and Forearm Section in Essentials of Muskuloskeletal Imaging, Eds. Johnson TR and Steinbach LS, AAOS, 2004.(2004)
• Bauer, G and Blaine, TA: Surgical Approaches to the Humerus in Fractures of the Shoulder Girdle, Eds. Levine WN, Marra G, and Bigliani, LU , 2003.(2003)
• Ahmad, CS, Freehill MQ, Blaine TA, Levine WN, Bigliani LU: Anteromedial Capsular Redundancy and Labral Deficiency in Shoulder Instability. AMERICAN JOURNAL OF SPORTS MEDICINE 31: 247-252, 2003.(2003)
• Park MC, Murthi AM, Roth NS, Blaine TA, Levine WN, Bigliani LU. Two-part and three-part fractures of the proximal humerus treated with suture fixation. JOURNAL OF ORTHOPAEDIC TRAUMA 17(5): 319-25, 2003.(2003)
• Bauer, G., Blaine, TA, and Bigliani, LU: Arthroscopic Debridement and Capsular Release in Master Techniques in Orthopaedic Surgery: Shoulder Arthroscopy, Eds. Tibone, Savoie, and Shaffer, B., 2003.(2003)
• Park, M., Blaine, TA, and Levine, WN: Shoulder Dislocation in Young Athletes: Current Concepts in Management, THE PHYSICIAN AND SPORTS MEDICINE, 30: 41-48, 2002.(2002)
• Carroll, R., Osgood, G., and Blaine, TA: Radial Head Fractures: Repair, excise, or replace?, CURR. OPIN. ORTHOP., 13(4):315-322, August, 2002(2002)
• Blaine, TA and Bigliani, LU: Arthroscopy for the Arthritic Shoulder, Orthopaedic Knowledge Update, Shoulder and Elbow, AAOS 2001.(2001)
• Blaine, TA and Sanchez-Sotelo, J: Radial Head Arthroplasty, SEMINARS IN ARTHROPLASTY, 12(2): 72-80, 2001.(2001)
• Murthi, A., Blaine, TA, and Bigliani, LU: Recurrent Multidirectional Instability after Inferior Capsular Shift in Contemporary Management of Complex Upper Extremity Disorders, Eds. Brems, J., 2001.(2001)
• Blaine, TA, Freehill, MQ, and Bigliani, LU.: Technique of Open Rotator Cuff Repair, in Instructional Course Lectures 50: 43-52, AAOS 2001.(2001)
• Blaine, TA and Bigliani, LU: Surgical Treatment of Shoulder Problems in Throwing Sports: Anterior Inferior Instability - Open Treatment, SPORTS MEDICINE AND ARTHROSCOPY REVIEW, 8(3): 305-314, 2000.(2000)
• Blaine, TA., Pollice, PF., Rosier, RN., Reynolds, PR., Puzas, JE., and O'Keefe, RJ. Modulation of cytokine production in titanium stimulated human monocytes by pharmacologic agents: the role of cAMP signaling mechanisms. The Journal of Bone & Joint Surgery, 79-A, 10:1519-28, October, 1997. MOSBY YEARBOOK OF ORTHOPAEDICS, 1998.(1997)
• Blaine, TA., Rosier, RN., Puzas, JE., Looney, RJ., Reynolds, PR., Reynolds, SD., and O'Keefe, RJ. Increased levels of tumor necrosis factor-alpha and interleukin-6 protein and messenger RNA in human peripheral blood monocytes due to titanium particles. THE JOURNAL OF BONE & JOINT SURGERY, 78-A, 8:1181-92, August, 1996.(1996)
• Peterson, DN., Blaine, TA., Lichtler, A., Rowe, DW., and Kream, BE. Glucocorticoid regulation of-1 collagen promoter constructs in stably transfected osteoblastic Py-1a cells. JOURNAL OF BONE & MINERAL RESEARCH, 6: S204, 1991.(1991)
• Taylor, T., Wondisfort, FE., Blaine, T., and Weintraub, BD. The paraventricular nucleus of the hypothalamus has a major role in thyroid hormone feedback regulation of thyrotropin synthesis and secretion. ENDOCRINOLOGY, 126:317-324, 1990.(1990)