Dr. Zhang had trainings in both medicine and biology before obtaining her Ph.D degree in biostatistics from University of Washington, Seattle. Since graduation, she had worked both in the academia and industry before joining Brown University. Her research interests focus on the biomarker evaluation, prediction model, personalized medicine in disease diagnosis, prognosis, and treatment, reproducibility and agreement methods.

Biography

Dr. Zhang had trainings in both medicine and biology before obtaining her Ph.D degree in biostatistics from University of Washington, Seattle. Since graduation, she had worked both in the academia and the pharmaceutical industry before joining Brown University. Her research interest is in cancer research, clinical trials, semi-parametric and non-parametric methods, diagnostic medicine, biomarker research, reproducibility and agreement methods.

Research Description

Dr. Zhang had trainings in both medicine and biology before obtaining her Ph.D degree in biostatistics from University of Washington, Seattle. Since graduation, she had worked both in the academia and industry before joining Brown University. Her research interests focus on the biomarker evaluation, prediction model, personalized medicine in disease diagnosis, prognosis, and treatment, reproducibility and agreement methods.

Awards

Donovan J. Thompson Award for Academic Excellence in Biostatistics
(Best performance in combined Ph.D. theory and applied qualifying exams)
University of Washington Department of Biostatistics 2001

Outstanding Student Award for best academic performance
Beijing University, Beijing, P. R. China 1987

Affiliations

American Statistical Association
International Biometric Society, Eastern North American Region
International Biometric Society, Western North American Region

Funded Research

1. U01 CA 079778 (Gatsonis) 03/02/99 – 12/31/12
NCI
Biostatistics Data Management Center for ACRIN

2. U01 CA 079778 (Gatsonis) 01/01/08 – 12/31/10
Foundation for the NIH
FDG-PET/CT as a Predictive Marker of Tumor Response and Patient Outcome: Prospective Validation in Non-small Cell Lung Cancer (ACRIN 6678)

Teaching Experience

Statistical method in designing and analyzing clinical trials

Courses Taught

• Clinical Trials Methodology (PHP2030)

Selected Publications

• Wolk D, Zhang Z, Boudhar S. etc (2012). Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography. Journal of Neurology, Neurosurgery and Psychiatry. doi:10.1136/jnnp-2012-302548(2012)
• Berg WA, Barr RG, and Zhang Z. (2012) Supplementary Imaging for Breast Cancer Screening in High-Risk Women—Reply. Journal of the American Medical Association. 308(3): 236-236. doi:10.1001/jama.2012.7549.(2012)
• Barr R and Zhang Z. (2012) Effects of Precompression on Elasticity Imaging of the Breast: Development of a Clinically Useful Semiquantitative Method of Precompression Assessment. Journal of Ultrasound in Medicine. 31: 895-902.(2012)
• Cole EB, Zhang Z, Marques H, et.al. (2012) Assessing the Stand-Alone Sensitivity of Computer-Aided Detection with Cancer Cases From the Digital Mammographic Imaging Screening Trial. American Journal of Roentgenology. 199: W1-9.(2012)
• Berg WA, Zhang Z, Lehrer DE, et.al. (2012) Detection of Breast Cancer with Addition of Annual Screening Ultrasound or a Single Screening MRI to Mammography in Women with Elevated Breast Cancer Risk. Journal of the American Medical Association. 307(13): 1394-1404. PMID: 22474203.(2012)
• Zhang Z, Huang Y (2012) A Linear Regression Framework for Receiver Operating Characteristic (ROC) Curve Analysis. Journal of Biometrics and Biostatistics. 3:137. doi: 10.4172/2155-6180. 1000137.(2012)
• Mosher TJ, Zhang Z, Reddy R, et. al. (2011) Knee Articular Cartilage Damage in Osteoarthritis: Analysis of MR Image Biomarker Reproducibility in ACRIN-PA 4001 Multicenter Trial. Radiology. 258: 832-842.(2011)
• Berg WA, Sechtin AG, Marques H and Zhang Z. (2010) Cystic Breast Masses and the ACRIN 6666 Experience. Radiol Clinics N Amer. 48: 931-987.(2010)