Applied surgical pathology of the head and neck and salivary glands.

Biography

I am a surgical pathologist with a strong interest and subspeciality expertise in head and neck and salivary gland pathology. I have written over 175 articles and book chapters most of which were in the field of head and neck and salivary gland pathology as well as edited 3 textbooks and have presented talks around the world on various topics in my subspeciality area. I continue to be involved in various applied research projects predominantly in my areas of subspecialization.

Institutions

Rih

Research Description

I am currently working on multiple applied research projects including the following:

1. Atypical carcinoid tumors of the major salivary glands;


2. The oncocytic variant of acinic cell carcinoma;


3. Unusual metaplastic lesions of the salivary glands;


4. Dedifferentiated tumors of the salivary glands;


5. Primary mucin producing tumors of the salivary glands: a clinicopathologic and morphometric study;


6. Localization of nanoparticle labelled lectins in various head and neck, breast, lung, and GI tumors.

Awards

Pi Tau Sigma (Mechanical Engineering Honorary Society) 1967
Tau Beta Pi (National Engineering Honorary Society) 1968
Phi Kappa Phi (National Honorary Society) 1968
Second Honors in Mechanical Engineering, Class Rank 2nd in 97 1969
Tau Beta Pi Fellowship 1969-1970
Robert Young Memorial Scholarship 1970
Scholar of the Leopold Schepp Foundation 1970-1971
Listed in The Best Doctors In America 1994-2012
Listed in Who's Who in Science and Engineering 1996-1997
Listed in Who's Who in Medicine and Healthcare 1997,1999-2000, 2006-2007
Listed in International Who's Who of Professionals 1999
Listed in Who's Who in the World 2000, 2004-2005
Listed in National Registry of Who's Who, Life Member 2001
Listed in Who's Who in Medicine and Healthcare 4th through 8th Editions 2002-2012
Listed in Who's Who in America 2003-2007
Invited Expert – WHO classification of Head and Neck Tumours
Consensus Conference/Editorial Review Board
International Agency for Research on Cancer, Lyon, France July 16-19, 2003
Honorary membership in the British Society of Oral Maxillofacial Pathology 2007
Listed in Cambridge Who's Who 2009/2010
America's Top Pathologists (Consumers' Research Council of America) 2009
Honorary Fellow of the American Academy of Oral and Maxillofacial Pathology 2011
Listed in Best Doctors in America, 2013 database.

Affiliations

Professor of Pathology, Brown University, Providence, Rhode Island, 1991-present

Pathologist, Department of Pathology, Rhode Island Hospital, 1991-present

Pathologist, Department of Pathology, Miriam Hospital, 2006

Funded Research

1. Department of Health & Human Services, Public Health Service, Center for Disease Control, Contract No. 200-85-0810: Selected Cancers Study, "Histologic Review of Nasal and Nasopharyngeal Carcinomas in Vietnam Veterans Exposed to Agent Orange", January 1984 through March 1990, $75,375.



2. National Organization for Rare Disorders, Inc., Dr. Cynthia L. Jackson and Dr. Douglas R. Gnepp: "Identification of a Gene Located at Chromosome 9p13 Important in Adenoid Cystic Carcinoma", April 2001 through September 2003, $80,000.

Selected Publications

• Skalova A, Gnepp DR, Simpson RH, Lewis JE, Janssen D, Michal M: Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor locus (HUMARA) as a marker. Amer J. Surg. Pathol. (In Press)(IN PRESS)
• Gnepp DR, Wang LJ, Brandwein-Gensler M, et al: Sclerosing polycystic adenosis of the salivary gland: a report of 16 cases. Amer J Surg Pathol. 30(2): 154-64, 2006.(2006)
• Gnepp, D. R.: Special techniques; Low grade cribriform cystadenocarcinoma; Carcinoma ex Mixed Tumor; Metastasizing Mixed Tumor; Carcinosarcoma; Soft Tissue Neoplasms; Benign and Malignant Sebaceous Neoplasms. In WHO Classification of Tumors: Pathology and Genetics of Head and Neck Tumors, Editors: L. Barnes, J. Eveson, P. Reichart, D. Sidransky. International Agency For Research on Cancer, Lyon, France, 2005(2005)
• Brandwein-Gensler M, Hille J, Wang BY, Urken M, Gordon R, Wang L, Simpson JR, Simpson RH, Gnepp DR: Low-Grade Salivary Duct Carcinoma – Description of 16 cases. Am.J.Surg. Pathol. 2004 Aug: 28(8): 1040-1044, 2004.(2004)
• Liu F, Gnepp DR, Pisharodi LR: Fine needle aspiration of parathyroid lesions. Acta Cytol 48: 133-6, 2004.(2004)
• O'Regan E, Shandilya M, Gnepp, DR, Timon C, Toner M: Hyalinizing clear cell carcinoma of salivary gland: an aggressive variant. Oral Oncology 40: 348-52, 2004.(2004)
• Shah, R.K., Gnepp, DR, Nigri, P.T.: Clinical Problem Solving: Pathology Laryngeal Chondrosarcoma. Archives of Otolaryngology. 130: 367, 369-70, 2004.(2004)
• Gnepp, D.R.: Commentary: Sclerosing Polycystic Adenosis of the Salivary Gland: A Lesion That May Be Associated With Dysplasia and Carcinoma In Situ. In Advances in Anatomic Pathology. 2003; 10(4): 218-222(2003)
• Zhu, K, Levine, RS, Brann, EA, Hall, I, Caplan, LS, Gnepp, DR: A case control study evaluating the homogeneity and heterogeneity of risk factors between sinonasal and nasopharyngeal cancers. Int. J. Cancer 99: 119-123, 2002.(2002)
• Diagnostic Surgical Pathology of the Head and Neck. D.R. Gnepp editor. W. B. Saunders Co., Philadelphia, 2001.(2001)
• Brandwein M, Ivanov K, Wallace D, Hille JJ, Wang B, Fahmy A, Bodian C, Urken ML, Gnepp D, Huvos A, Lummerman H, Mills M: Salivary mucoepidermoid carcinoma: A clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol 25: 835-45, 2001.(2001)
• McGough R, Wang LJ, Gnepp D, Terek RM. Metastatic Mixed Tumor Arising in Bone. A Case Report and Review of the Literature. J. Bone and Joint Surgery. 83: 1396 – 1402, 2001.(2001)
• Brandwein M, Hille JJ, Gnepp D, Urken ML, Ivanov K: The Many Faces of Mucoepidermoid Carcinoma. Pathology Case Reports. 5 (4): 214 – 220, 2000.(2000)
• Zarbo, RJ, Barnes, L, Crissman, JD, Gnepp, DR, Mills, SE and the Association of Directors of Anatomic and Surgical Pathology: Recommendations for the Reporting of Specimens Containing Oral cavity and Oropharynx Neoplasms. American Journal of Clinical Pathology –114:336-338, 2000 and Human Pathol 31: 1191-3,2000.(2000)
• Gnepp DR, Souther J: Skeletal muscle in routine tonsillectomy specimens, a common finding. Human Pathol 31: 813-16, 2000.(2000)
• Bouquot JE, Gnepp DR, Dardick I, Hietanen JHP: Intraosseous salivary tissue: Jawbone examples of choristomas, hamartomas, embryonic rests and inflammatory entrapment. Another histogenetic source for intraosseous adenocarcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 90:205-17, 2000.(2000)
• Henley J, Seo IF, Dayan D, Gnepp DR: Sarcomatoid salivary duct carcinoma of the parotid gland. Human Pathol 33:208-213, 2000.(2000)
• Surgical Pathology of the Salivary Glands. G.L. Ellis, P.L. Auclair, D. R. Gnepp editors. In the Major Problems in Pathology Series, V25, W.B. Saunders Co, Philadelphia, 1991.(1991)
• Pathology of the Head and Neck. D.R. Gnepp editor, In the Contemporary Issues in Surgical Pathology Series, series editor, L. Roth, Churchill Livingstone, Inc., New York, 1988.(1988)