Biography

Silvia Degli Esposti, MD, is director of the Center for Women's Gastrointestinal Medicine at the Women's Medicine Collaborative. She is an associate professor of medicine (clinical) at The Warren Alpert Medical School of Brown University and director of the fellowship pathway in women's gastrointestinal diseases at Alpert Medical School. Degli Esposti graduated summa cum laude from the University of Bologna Medical School in Bologna, Italy. She completed her residency and fellowship at Brown University.

She was the director of the Division of Gastroenterology and the gastrointestinal disorders in pregnancy clinic at Women & Infants before moving to the Women's Medicine Collaborative.

Degli Esposti is board certified in internal medicine and gastroenterology. Her clinical and research interests include liver disease and gastrointestinal diseases in women. She is currently leading several studies in inflammatory bowel disease and hepatitis in pregnancy.

Dr. Degli Esposti is an active staff member of not only Women & Infants Hospital, but of Roger Williams Medical Center, Kent County Hospital, Rhode Island Hospital and Miriam Hospital.

Dr. Degli Esposti has written numerous publications. Her current publications include a chapter written for the 5-Minute Consult Clinical Companion to Women's Health on Cirrhosis and a chapter written for the American College of Physician's textbook Medical Care of the Pregnant Patient, 2nd Edition entitled "Liver Disease in Pregnancy".

Her teaching roles include Director of the Women's Gastrointestinal Disorder (Fellowship Tract) at Brown University, Course Director of the Elective for Gastroenterology Fellowship at Brown University Medical School entitled "Gastroenterology in Women's Health and Pregnancy", Small Group Leader of the Patholophysiology of the GI Tract and Liver – Bio 282. She is a mentor for the Obstetric Medicine and Maternal Fetal Medicine Fellowship Program and heads the elective for the Gastroenterology Fellowship at Rhode Island Hospital.

Institutions

Wih

Research Description

RESEARCH

1. "A Multi-Center National Prospective Study of Pregnancy and Neonatal Outcome in Women with Inflammatory Bowel Disease", CCFA/CRA . Principal Investigators: Silvia Degli Esposti, MD, Sumona Saha, MD. Selected Site. 2007-2009.

2. Enteral nutrition by jejunostomy in severe hyperemesis gravidarum: a case series of one institution's experience (Inactive). Principal Investigator: Sumona Saha, MD; Key Personnel: Silvia Degli Esposti, MD.

3. Microsatelite instability and hmlh1/hmsh2/hmsh6 expression in patients with endometrial cancer: are cases of hnpcc being missed? (Active). Principal Investigator: Silvia Degli-Esposti, MD

4. A multi-center national prospective study of pregnancy and neonatal outcomes in women with inflammatory bowel disease. (Active). Principal Investigator: Silvia Degli-Esposti, MD.

5. GI consultations in pregnancy (Inactive). Principal Investigator: Sumona Saha, MD; Key Personnel: Silvia Degli Esposti, MD.

6. OSCCAR: Ocean State Crohn's & Colitis Area Registry. Funded by the National Institutes of Health (NIH). This study is being conducted in joint collaboration between Lifespan and Massachusetts General Hospital. Silvia Degli Esposti, MD is the Women & Infants Hospital sponsr for this study.

Awards

POSTGRADUATE HONORS AND AWARDS

1985 Postdoctoral Fellowship Award, American Liver Foundation.

1986 Harvey Lesselbaum Award, Miriam Hospital, Providence, RI.

1987 Grande Croce al merito per la Sanita, Istituto Internazionale per le Scienze Socio-Economiche. Rome, Italy (Cross for Special Value in the Health Science, International Institute for Socio-Economic Science).

1995 Award for Best Presentation by the Italian Association for the Study of Liver Disease, Rome, Italy.

1999 "Vision to Action Award" American National Academy of Psychologists.

2000 Resident Excellence in Teaching Award, Women & Infants Hospital.

2002,2003,2004, Dean's Teaching Excellence Award –Bio282
2005,2006,2007 Pathophysiology/Gastroenterology
Alpert Medical School of Brown University

2007 Voted "Best Gastroenterologist for Women". Rhode Island Magazine, RI.

March 2009 The Rhode Island Perinatal Hepatitis Prevention Program, a collaborative effort of Women & Infants Hospital (Center for Women's Gastrointestinal Services), Hasbro Children's Hospital, the VNA of Care New England, and the Rhode Island Department of Health, was recently recognized by the Centers for Disease Control and Prevention. Rhode Island has the highest immunization rate in the country – 95% for three doses in the first eight months of life – of infants born to women with hepatitis B.

May 2009 Voted "Best Gastroenterologist for Women". Rhode Island Magazine, RI.

Affiliations

1988-Present American Association for the Study of Liver Disease (AASLD)

1988-1992 American Association for the Advancement of Science

1988-1992 American Federation for Clinical Research, New York Academy of Science

1999-Present Rhode Island Medical Women's Association (RIMWA)

7/2000-Present Rhode Island Medical Society (RIMS)

6/2007-Present American College of Gastroenterology (ACG)

11/2007-Present Crohn's and Colitis Foundation of America (CCFA)

Funded Research

Title: A Multi-center National Prospective Study of Pregnancy and Neonatal Outcomes in Women with IBD (IBD in Pregnancy)
Funding: Crohn's Colitis Foundation of America (CCFA)
Summary: This study is conducted to determine whether the rates of birth defects, miscarriages, premature births, and other outcomes in women with inflammatory bowel disease (IBD) exposed to azathioprine/6MP or anti TNF therapy (Remicade, Humara, Cimzia) are greater than those among IBD affected women not taking these medications. The secondary purpose of this study is to create a national prospective pregnancy registry among members of the CCFA Clinical Research Alliance to study pregnancy and neonatal outcomes.
Patients are identified by the GI practice at Women & Infants' Hospital.
For referral information please call 401-274-1122 and speak with Susan Martin (ext.7353).
Dates: 8/2007-1/2010
PI: Silvia Degli-Esposti, MD, Sumona Saha, MD

Teaching Experience

HOSPITAL TEACHING ROLES

1997-present Lecturer, Core Curriculum, Hepatology - Gastroenterology, Women & Infants' Program in Obstetrics and Gynecology .

1997-present Lecturer, Nurse Practitioner, WPCC.

1997-present Lecturer, Obstetric Medicine and Maternal Fetal Medicine,Fellowship program.

2000-present Elective for Gastroenterology Fellowship at Rhode Island Hospital.

2001 Mentor, fourth year research project for obstetric and gynecology resident, "Hyperemesis Gravidarum and Helicobacter Pylori Infection".

2004-present Director of Women's Gastrointestinal Disorder (Fellowship Tract), The Warren Alpert Medical School of Brown University.

Courses Taught

• Pathophysiology (Bio 282)
• Pathophysiology/Pharmacology - GI Section Course (Bio 351)

View My Full Publication List in pdf format

Selected Publications

• Degli Esposti S, Goodwin TM, Pickard J, Reily CA, Reyes H. Liver Disease. In: Rosene-Montella K, Keely E, Barbour LA, Lee RV, eds. Medical Care of the Pregnant Patient. 2nd ed. Philadelphia, PA: American College of Physicians;2008:567-593.(2008)
• Saha S, Degli Esposti S. Cholestasis of Pregnancy. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia,PA: Lippincott, Williams and Wilkins;2007:226-228.(2007)
• Saha S, Degli Esposti S. Acute Fatty Liver of Pregnancy. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:247-249.(2007)
• Degli Esposti S. Hepatitis C. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:135-137.(2007)
• Degli Esposti S. Hepatitis B. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins; 2007:132-134.(2007)
• Kelly C, Degli Esposti S. Hyperemesis. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:238-240.(2007)
• Lenzi M, Degli Esposti S. Autoimmune Hepatitis. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:36-38.(2007)
• Saha S, Degli Esposti S. Celiac disease. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:56-58.(2007)
• Cantarini MC, Degli Esposti S. Cirrhosis. In: Kelly A. McGarry & Iris L. Tong (eds). 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA; Lippincott, Williams & Wilkins;2007;63-65.(2007)
• Degli Esposti S. Non Alcoholic Fatty Liver. In: McGarry KA, Tong IL, eds. 5-Minute Consult Clinical Companion to Women's Health. Philadelphia, PA: Lippincott, Williams and Wilkins;2007:180-182.(2007)