Cartilage Repair

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TISSUE ENGINEERED THERAPIES VS. STANDARD OF CARE: for a competitive athlete's needs

 

TREATMENT

ADVANTAGES

DISADVANTAGES

Arthroscopic Shaving or Debridement

  • minimally invasive
  • cost-effective
  • short rehabilitation time
  • recurring symptoms
  • shoulder instabliity
  • chronic deterioration
Microfracture
  • cost-effective
  • technically feasible
  • clinical data: Dr. Steadman reported improvements in function and symptoms of 75% of patients, average 7 years post operation (n=485) (Steadman-Hawkins Clinic)
  • does not reliably produce hyaline cartilage
  • restriction of mobility
  • lack of strength leading to instability
OATS
  • high survival rate of articular chondrocytes
  • hyaline cartilage characteristics
  • donor site morbidity
  • long rehabilitation
  • articular surface injury due to plug implantation leading to inflammation and joint mobility restriction
Osteochondral Allografts Resurfacing
  • high survival rate of articular chondrocytes
  • hyaline cartilage characteristics
  • immunological reaction and disease transmission
  • cell viability and fixation problems
  • limited supply of grafts
  • long rehabilitation
  • articular surface injury due to plug implantationleading to inflammation and joint mobility restriction
ACI/ACT
  • hyaline cartilage repair and characteristics
  • autologous cell implantation
  • less post-restriction in range of motion
  • one time treatment
  • restricted activity for 1 year to allow cell integration
  • expensive
  • two surgeries

 

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Created by: Blair Smith, Connie Lee, Daniel Solomon, Matthew Whitson and Stephanie Chang
Date last modified: 5/2/2004