REFERENCES

Overview of Stem Cells

  1. Shamblott, M.J., et al., Proceedings of the National Academy of Science, USA, 95, 13726 (1998).
  2. Thomson, J.A., et al. Science. 282, 1145-1147 (1998).

Hematopoetic Stem Cells

  1. Hancock, Johns Hopkins Magazine. (June 1996).
  2. ibid.
  3. ibid.
  4. Cord Blood Registry http://www.cordblood.com
  5. Lerner, M. Minneapolis Star Tribune. (Dec 14 1999).
  6. Cord Blood Registry
  7. American Cord Blood Program http://www.americancordblood.com
  8. UCLA Umbilical Cord Blood Bank http://www.cordblood.med.ucla.edu
  9. Cord Blood Registry

Embryonic Stem Cells

  1. Geron Corporation http://www.geron.com
  2. Lanza et al., Nature Biotechnology. 17 (Dec 1999).

Neural Stem Cells

  1. Hoffman, P. "Can I grow a new brain?" Layton BioScience, Inc. November 9, 1999. <www.laytonbio.com> (April 20, 2000).
  2. Strobel, G. "Neural stem cells raise prospect of repairing brain." Focus January 22, 1999. <www.med.harvard.edu/publications/Focus> (April 14, 2000).

Alzheimer's Disease

  1. Bovsun, M. "Stem cells calm shivering mice, may yield brain disease therapy." Biotechnology Newswatch. June 21, 1999.

Bone/Cartilage Replacement

  1. Vogel, G., "Harnessing the power of stem cells." Science. 283, 1432 (1999).

Bone Marrow Transplants

  1. "The Nuts and Bolts of Bone Marrow Transplants." BMT Newsletter. www.bmtnews.org/bmt/bmt.book/chapter.1.html (April 23, 2000).
  2. ibid.
  3. "Bone Marrow and Stem Cell Transplantation." Leukemia Research Fund www.leukaemia.demon.co.uk/bmt.htm (April 23, 2000).
  4. ibid.

Cancer

  1. Hancock, Elise "Stalking the Stem Cell." Johns Hopkins Magazine. 5/96 www.jhu.edu/~jhumag/696web/stemcell.html (April 23, 2000).
  2. "Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation." National Cancer Institute. 4/98 www.meb.uni-bonn.de/cancernet/400110.html (April 30, 2000).
  3. "Peripheral Blood Stem Cells for Allogeneic and Autologous Transplants." MD Anderson Cancer Center. 5/98 www.mdacc.tmc.edu/~bmt/stemcells.html (April 22, 2000).
  4. "New Option for Marrow Donors." Blood and Marrow Transplant Newsletter. 11/96 www.bmtnews.org/newsletters/issue46/option.html (April 24, 2000).

Cardiac Tissue

  1. Klug, et al, J Clin Invest 98: 216-224 (1996).

Diabetes

  1. Ramiya, V.K., et al. "Reversal of Insulin-depended diabetes using islets generated in vitro from pancreatic stem cells." Nature Med. 6, 278-282 (2000).
  2. Sachs, D.H., Bonner-Weir, S. "New islets from old." Nature Med. 6, 250-251 (2000).

Epilepsy

  1. National Institute of Neurological Disorders and Stroke www.ninds.nih.gov

Eye Trauma

  1. "Coming Out of the Dark: Second Chance for Sight." UCI Medical Group. 1/12/00 www.ucihealth.com (April 25, 2000).
  2. "Research Summary." Schepens Eye Research Institute. www.vision.research.training.harvard.edu (April 25, 2000).
  3. Pellegrini G, Traverso CE, Tito F. "Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium." The Lancet. 349, 990-993 (1997).
  4. Ibid.
  5. "Transplants for the Eye May Work to Cure Blindness." Medical Industry Today. June 4, 1999.
  6. Pellegrini G, Traverso CE, Tito F. "Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium." The Lancet. 349, 990-993(1997).
  7. Senior K. "New Hope reported for badly damaged eyes." The Lancet. 353, 2045 (1999).

Gene Therapy

  1. Kolata,Gina, "In a First, Gene Therapy Saves Lives of Infants", The New York Times. (April 28, 2000).
  2. "Stem cells could help in cancer, spine injury", Health Headlines. (April 11, 2000).

Infertility

  1. Ogawa, T., et al. "Transplantation of male germ line stem cells restores fertility in infertile mice." Nature Med. 6, 29-34 (2000).

Liver Disease

  1. "Bone marrow begets functioning liver cells." Medical Materials Update. 6 (1999).

Multiple Sclerosis

  1. Steghaus-Kovac, S. "Stem cells as potential nerve therapy." Science. 285, 650 (1999).

Muscular Dystrophy

  1. Muscular Dystrophy Association. http://www.mdausa.org
  2. Ferrari, G, et al. "Muscle regeneration by bone marrow-derived myogenic progenitors." Science. 279, 1528-1530 (1998).
  3. Wade, N. "Researchers Turn Marrow into Muscle." NY Times. Science/Health. (Sept. 23, 1999).

Parkinson's Disease

  1. Barinaga, M. "Fetal neuron grafts pave the way for stem cell therapies." Science. 287, 1421-1422 (2000).
  2. - - - -. "Brain cells grown, implanted in rats to treat Parkinson's." Medical Industry Today. (July 22, 1998).

Sickle Cell Anemia

  1. "A Cure For High-Risk Sickle Cell." Children's Healthcare of Atlanta. 12/13/99 www.choa.org/media/keone.shtml (May 1, 2000).
  2. ibid.
  3. "What is Sickle-Cell Disease?" Web MD 5/98 www.webmd.lycos.com/content/dmk/dmk_article_4007 (May 1, 2000).

Skin Trauma

  1. Davis, Alison "Supported Basic Research on Skin Replacement Following Burn or Trauma Injury." National Institute of General Medical Sciences. 5/18/99. www.nigms.nih.gov/news/features/artificial_skin.html (April 27,2000).
  2. ibid.
  3. ibid.
  4. Rosner, Elsie "Hidebound." Physicians Weekly. 5/22/96. www.physweekly.com/archive/96/07_22_96/twf.html (April 27,2000).
  5. Neergaard, Lauren "FDA advisers back bioengineered skin implants." Seattletimes.com. 1/30/98 http://seattletimes.com/news.health-science/html98/skin_013098.html (April 25,2000).
  6. ibid.

Spinal Cord Injury

  1. Wickelgran, I. "Rat spinal cord function partially restored." Science. 286, 1826-1827 (1999).

Tay Sachs Disease

  1. Laino, C. "'Smart' tissue regenerates brain." MSNBC. www.msnbc.com. (April 28,2000).

On the Horizon

  1. Advanced Cell Technologies www.advancedcell.com/StemCellResearch.htm
  2. Weissman, Irving L. "Translating Stem and Progenitor Cell Biology to the Clinical: Barriers and Opportunities." Science. 287 (5457): 1442.
  3. Brooksbank, Catherine. "Hope, not hype, for the future of stem-cell-based therapies." Molecular Medicine Today. (January 1999).
  4. Bodnar, et al. "Extension of Life-Span by Introduction of Telomerase into Normal Human Cells." Science. 279, 349-352 (1998).
  5. Nowak, Rachel. "Decision time: A single protein may be the first step to customizing human stem cells." New Scientist. (April 8, 2000).

Obstacles to Overcome

  1. "Harnessing the Power of Stem Cells." Science. 283, (1999).
  2. ibid.
  3. ibid.
  4. Lanza, et al. "Prospects for the use of nuclear transfer in human transplantation." Nature Biotech. 17, (Dec 1999).
  5. Sheilds, PG, et al. "Analysis of Telomere length in cloned sheep." Nature. 399, 316-317, (1999).
  6. Solter, et al. "Putting stem cells to work." Science. 283, (1999).
  7. ibid.
  8. Lanza, et al.

Legal and Ethical Issues

  1. Whiting, Sarah. "The Stem Cell Debate." The Department of Bacteriology at UWM. (July 28, 1999). www.bact.wisc.edu/ScienceEd/thestemcelldebate.html. (May 1, 2000).
  2. Pedersen, Robert A; "Ethics and Embryonic Cells." Scientific American. (April 1999), 71.
  3. Caplan, Arthur L. Prepared statement given at Environment and Health subcommittee (to S. Appropriations committee) hearing. (Dec. 2, 1998).
  4. Hall, Stephen S. "The Recycled Generation." The New York Times Magazine. (Jan. 30, 2000), 35.
  5. Alper, Joseph. "A Man in a Hurry." Science. 283, 1434, (1999).
  6. Hall, 35.
  7. Prepared statement given at Environment and Health subcommittee (to S. Appropriations committee) hearing. (Dec. 2, 1998).
  8. Hall, 75.
  9. NIH Director's Statement on Research Using Stem Cells - 12/1/99. www.nih.gov/news/stemcell/draftguidelines.htm. (April 22, 2000).
  10. "Draft National Institutes of Health Guidelines for Research Involving Human Pluripotent Stem Cells." www.nih.gov/news/stemcell/draftguidelines.htm. (April 22, 2000).
  11. U.S. Senate: www.senate.gov
  12. Perry, Daniel. "Patients' Voices: The Powerful Sound in the Stem Cell Debate." Science. 287, 1423, (2000).