Brown University Department of Pathology and Laboratory Medicine
Research

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Human diseases are complex, multistage processes that evolve over years or even decades. Both endogenous or genetic factors and exogenous or environmental factors can contribute to or modify these disease processes. Traditionally, pathologists have been involved in establishing the diagnosis and determining prognostic criteria for disease using morphologic and biochemical techniques. Modern experimental pathologists integrate classical morphologic techniques with new approaches using powerful new tools for quantitative imagining and molecular analysis of human tissue opening up an exciting new era of research in pathology.

The integration between biology and medicine at Brown University provides a unique environment for interdisciplinary research initiatives that include pathologists. Faculty in the Department of Pathology and Laboratory Medicine are trained in the cellular, biochemical, and molecular mechanisms of disease that provide the foundation for basic, translational, and clinical research. Basic research programs focus on environmental health and disease including cancer, reproductive and genetic toxicology, and neurodegenerative disease. Interdisciplinary translational and clinical research initiatives include nanotechnology, diagnostic and prognostic markers for cancer, developmental and perinatal pathology, medical screening and prenatal genetic testing, transgenic models of human disease, infectious disease and host response to malaria, schistosomiasis, and herpesvirus, and clotting disorders and transfusion medicine. These interdisciplinary research initiatives include faculty in the Division of Engineering and the Departments of Clinical Neurosciences, Medicine, Surgery, Pediatrics, and Obstetrics and Gynecology at Brown University.

Faculty in the Department of Pathology and Laboratory Medicine have funded biotechnology initiatives in tissue engineering, cell transplantation, and gene therapy.


Last updated: September 6, 2011 |   Questions & Comments: Beth_Martin@brown.edu