Brown University Department of Pathology and Laboratory Medicine
Superfund Basic Research Program

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www.brown.edu/sbrp

This is an interdisciplinary research, educational, and outreach effort directed by Kim Boekelheide, M.D., Ph.D. focused on mechanisms of disease and chemical and physical properties of mixed exposures encountered at toxic waste sites and Brownfields in Rhode Island. A major goal of this project is to develop and apply basic remediation technologies and strategies for local and regional communities. This collaborative effort involves Brown University faculty and students as well as state agencies and community outreach. This new grant provides a unique opportunity for faculty and students to work together on a challenging scientific and technical problem that has significant impact in Providence and Rhode Island.

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Mouse sperm immunostained for Raf Kinase Inhibitor Protein (RKIP). We are investigating the importance of RKIP as a master regulator of sperm function. Studies suggest that environmental toxicants can modulate the expression of this protein, possibly leading to impaired fertility.


Last updated: September 6, 2011 |   Questions & Comments: Beth_Martin@brown.edu